Probe:

Akr1a4 cDNA

Structure	Level	Pattern	Image	Note
TS11: embryo	Weak		2B	Broadly expressed.

Structure	Level	Pattern	Image	Note
TS13: neural ectoderm	Strong		2C
TS13: embryo mesenchyme	Weak	Regionally restricted	2C	Expression is in mesenchyme at the level of the open neural tube.

Structure	Level	Pattern	Image	Note
TS13: neural ectoderm	Strong		2D
TS13: embryo mesenchyme	Weak	Regionally restricted	2D	Expression is in mesenchyme at the level of the open neural tube.

Structure	Level	Pattern	Image	Note
TS13: gut endoderm	Strong		2E
TS13: neural ectoderm	Strong		2E

Structure	Level	Pattern	Image	Note
TS13: neural ectoderm	Strong		2F
TS13: trunk somite	Weak		2F

Structure	Level	Pattern	Image	Note
TS14: central nervous system	Present		2G
TS14: gut	Present	Regionally restricted	2G	Expression is in the gut endoderm.
TS14: otic placode	Strong		2G

Structure	Level	Pattern	Image	Note
TS14: central nervous system	Present		2H
TS14: gut	Present	Regionally restricted	2H	Expression is in the gut endoderm.
TS14: 1st branchial arch ectoderm	Strong		2H
TS14: otic placode	Strong		2H

Structure	Level	Pattern	Image	Note
TS14: central nervous system	Present		2I
TS14: gut	Present	Regionally restricted	2I	Expression is in the gut endoderm.

Structure	Level	Pattern	Image	Note
TS14: central nervous system	Present		2J
TS14: gut	Present	Regionally restricted	2J	Expression is in the gut endoderm.
TS14: tail bud	Strong	Regionally restricted	2J	High levels of expression in the ectoderm overlying the tail bud mesenchyme.

Structure	Level	Pattern	Image	Note
TS15: limb	Strong		2K
TS15: branchial arch	Strong		2K
TS15: fronto-nasal process	Strong		2K
TS15: otocyst	Strong		2K
TS15: tail	Strong		2K

Structure	Level	Pattern	Image	Note
TS15: branchial arch	Strong		2L
TS15: fronto-nasal process	Strong		2L
TS15: otocyst	Strong		2L
TS15: tail	Strong		2L
TS15: neural tube	Weak		2L

Structure	Level	Pattern	Image	Note
TS17: branchial arch	Strong		2M
TS17: fronto-nasal process	Strong		2M
TS17: otocyst	Strong		2M
TS17: tail	Strong		2M
TS17: neural tube	Absent		2M

Structure	Level	Pattern	Image	Note
TS19: limb ectoderm	Strong		2N	Expression localized in the ectoderm and underlying mesoderm of the limb buds.
TS19: limb mesenchyme	Strong		2N	Expression localized in the ectoderm and underlying mesoderm of the limb buds.
TS19: tail	Strong		2N
TS19: surface ectoderm	Weak	Regionally restricted	2N	Expression is in the trunk region.
TS19: trunk mesenchyme	Weak		2N
TS19: head	Weak	Regionally restricted	2N	Expression in the facial region is declining.

Structure	Level	Pattern	Image	Note
TS19: limb ectoderm	Strong		2O	Expression localized in the ectoderm and underlying mesoderm of the limb buds.
TS19: limb mesenchyme	Strong		2O	Expression localized in the ectoderm and underlying mesoderm of the limb buds.
TS19: surface ectoderm	Weak	Regionally restricted	2O	Expression is in the trunk region.
TS19: trunk mesenchyme	Weak		2O

Structure	Level	Pattern	Image	Note
TS19: surface ectoderm	Weak		2P	Expression is in the trunk region.
TS19: trunk mesenchyme	Weak		2P

Structure	Level	Pattern	Image	Note
TS20: head	Weak	Regionally restricted	2Q	Expression in the facial region is declining.
TS20: limb epithelium	Present	Regionally restricted	2Q	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS20: limb interdigital region mesenchyme	Present		2Q	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS20: limb epithelium	Present	Regionally restricted	2R	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS20: limb interdigital region mesenchyme	Present		2R	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS21: head	Weak	Regionally restricted	2S	Expression in the facial region is declining.
TS21: limb epithelium	Present	Regionally restricted	2S	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS21: limb interdigital region mesenchyme	Present		2S	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS21: limb epithelium	Present	Regionally restricted	2T	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS21: limb interdigital region mesenchyme	Present		2T	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS19: forelimb bud ectoderm	Strong		3A	High levels of expression localized in the ectoderm and underlying mesoderm.
TS19: forelimb bud mesenchyme	Strong		3A	High levels of expression localized in the ectoderm and underlying mesoderm.

Structure	Level	Pattern	Image	Note
TS20: limb epithelium	Present	Regionally restricted	3B	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS20: forelimb interdigital region mesenchyme	Present		3B	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS21: hand epithelium	Present	Regionally restricted	3C	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS21: forelimb interdigital region mesenchyme	Present		3C	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS22: hindlimb digit skin	Present	Regionally restricted	3D	Expression restricted to the edges of the presumptive digits.

Structure	Level	Pattern	Image	Note
TS22: forelimb	Absent

Structure	Level	Pattern	Image	Note
TS15: forelimb bud	Strong		3E

Structure	Level	Pattern	Image	Note
TS19: forelimb bud ectoderm	Strong		3F	High levels of expression localized in the ectoderm and underlying mesoderm.
TS19: forelimb bud mesenchyme	Strong		3F	High levels of expression localized in the ectoderm and underlying mesoderm.

Structure	Level	Pattern	Image	Note
TS20: hand epithelium	Present	Regionally restricted	3G	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS20: forelimb interdigital region mesenchyme	Present		3G	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS21: hand epithelium	Present	Regionally restricted	3H	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.
TS21: forelimb interdigital region mesenchyme	Present		3H	Expression in the developing limbs became more restricted to the distal ectoderm and interdigital mesenchyme.

Structure	Level	Pattern	Image	Note
TS21: lung mesenchyme	Weak		3I	Low background expression throughout the lung mesenchyme.
TS21: lung	Strong	Regionally restricted	3I	Markedly elevated expression in the segmental bronchi.

Structure	Level	Pattern	Image	Note
TS21: lung mesenchyme	Weak		3J	Low background expression throughout the lung mesenchyme.
TS21: lung	Strong	Regionally restricted	3J	Markedly elevated expression in the segmental bronchi.

Structure	Level	Pattern	Image	Note
TS22: lung mesenchyme	Weak		3K	Low background expression throughout the lung mesenchyme.
TS22: lung	Strong	Regionally restricted	3K	Markedly elevated expression in the terminal bronchi.

Structure	Level	Pattern	Image	Note
TS22: lung mesenchyme	Weak		3L	Low background expression throughout the lung mesenchyme.
TS22: lung	Strong	Regionally restricted	3L	Markedly elevated expression in the terminal bronchi.