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Gene Expression Data
Assay Details
Assay
Reference: J:74631 Tian E, et al., Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
Assay type: RNA in situ
MGI Accession ID: MGI:2179007
Gene symbol: En2
Gene name: engrailed 2
Probe: En2 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present 4K
TS15: future hindbrain Present Regionally restricted 4K Expression in anterior metencephalon.

Specimen 4L: embryonic day 9.5; Otx2tm1Sia/Otx2tm4Sia (more )
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 4L Authors report expression shifted anteriorly compared with wild type; not expressed in most anterior neurectoderm.

Specimen 5I: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain Present 5I
TS13: future hindbrain Present Regionally restricted 5I Expression in anterior metencephalon.

Specimen 5J: embryonic day 8.5; Otx2tm1Sia/Otx2tm4Sia (more )
Structure Level Pattern Image Note
TS13: future brain Present Regionally restricted 5J Authors report expression shifted anteriorly compared with wild type; not expressed in most anterior neurectoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory