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Gene Expression Data
Assay Details
Assay
Reference: J:73067 Li JY, et al., Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development. 2001 Dec;128(24):4979-91
Assay type: RNA in situ
MGI Accession ID: MGI:2158708
Gene symbol: Gbx2
Gene name: gastrulation brain homeobox 2
Probe: Gbx2 cDNA2
Probe preparation: Antisense RNA
Assay notes: This probe includes coding sequence that is 5' to the deletion in the mutant allele.
Results
Specimen 1A left: embryonic day 7.5 (more )
Note: This embryo was at early head fold.
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 1A left Expression is present in the posterior neuroectoderm.
Specimen 1A right: embryonic day 7.5; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: This embryo was at early head fold.
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 1A right Authors state that expression was comparable to that of wild type embryos, although lateral expression appears slightly expanded anteriorly.
Specimen 1B left: embryonic day 8.0 (more )
Note: This embryo was at late head fold.
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 1B left
Specimen 1B right: embryonic day 8.0; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: This embryo was at late head fold.
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 1B right Expression is significanly expanded anteriorly in the mutant embryo.
Specimen 1E left: embryonic day 7.5 (more )
Note: This embryo was at early head fold.
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 1E left Expression is present in the posterior neuroectoderm.
Specimen 1E right: embryonic day 7.5; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: This embryo was at early head fold.
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 1E right The expression is the same as in wild-type embryos; there is staining in the posterior neurectoderm.
Specimen 1F left: embryonic day 8.0 (more )
Note: This embryo was at late head fold.
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 1F left
Specimen 1F right: embryonic day 8.0; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: This embryo was at late head fold.
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 1F right Expression is significantly reduced in the mutant relative to wild-type, and its anterior limit of expression is shifted posteriorly/caudally.
Specimen Not shown: embryonic day 8.5; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Structure Level Pattern Image Note
TS13: embryo Present Expression is greatly reduced in the mutant relative to wild-type embryos.
Specimen 2A left: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 2A left
Specimen 2A right: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 2A right
Specimen 2B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory