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Gene Expression Data
Assay Details
Assay
Reference: J:70745 Suda Y, et al., Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
Assay type: RNA in situ
MGI Accession ID: MGI:2148278
Gene symbol: Otx1
Gene name: orthodenticle homeobox 1
Probe: Otx probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present 2M
TS19: diencephalon Present 2M
TS19: midbrain Present Regionally restricted 2M Most intense expression in anterior pretectum, tegmentum and boundary region along the zona limitans region.
Specimen 2N: embryonic day 11.5; Emx2tm1Sia/Emx2tm1Sia, Otx2tm1Sia/Otx2+ (more )
Note: Emx2 and Otx2 heterozygotes were maintained by crosses with CBA mice. Single Emx2 and Otx2 heterozygotes (from F3 and F5 generations, respectively) were mated to generate double heterozygotes, which were subsequently mated to generate the double mutants.
Structure Level Pattern Image Note
TS19: telencephalon Present 2N
TS19: diencephalon Present 2N
TS19: midbrain Present Regionally restricted 2N No expression in anterior pretectum and zone limitans region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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