Otx2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:69855 Martinez-Morales JR, et al., Otx genes are required for tissue specification in the developing eye. Development. 2001 Jun;128(11):2019-30
Assay type:	RNA in situ
MGI Accession ID:	MGI:2137339
Gene symbol:	Otx2
Gene name:	orthodenticle homeobox 2

Probe:	Otx2 cDNA1
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

1C ©

Specimen 1C: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: optic vesicle	Present	Regionally restricted	1C	Expression is predominant in the dorsal part.

1F ©

Specimen 1F: embryonic day 10.0 (more

)

Structure	Level	Pattern	Image	Note
TS15: eye	Present	Regionally restricted	1F	Expression is predominant in the dorsal part.

1I ©

Specimen 1I: embryonic day 11.0 (more

)

Structure	Level	Pattern	Image	Note
TS18: pigmented retinal epithelium	Present		1I

1L ©

Specimen 1L: embryonic day 12.0 (more

)

Structure	Level	Image
TS20: pigmented retinal epithelium	Present	1L
TS20: neural retinal epithelium	Absent	1L
TS20: optic stalk	Absent	1L

1O ©

Specimen 1O: embryonic day 12.5 (more

)

Structure	Level	Image
TS20: pigmented retinal epithelium	Present	1O
TS20: neural retinal epithelium	Absent	1O
TS20: optic stalk	Absent	1O

1R ©

Specimen 1R: embryonic day 13.5 (more

)

Structure	Level	Image
TS21: pigmented retinal epithelium	Present	1R
TS21: neural retinal epithelium	Absent	1R
TS21: optic nerve	Absent	1R

1U ©

Specimen 1U: embryonic day 16.0 (more

)

Structure	Level	Image
TS24: pigmented retinal epithelium	Present	1U
TS24: neural retina	Absent	1U
TS24: optic nerve	Absent	1U

3A ©

Specimen 3A: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: optic vesicle	Present	Regionally restricted	3A	Expression is in the dorsal half.

3B ©

Specimen 3B: embryonic day 9.5; Otx1^tm1Asim/Otx1^tm1Asim (more

)

Structure	Level	Pattern	Image	Note
TS15: optic vesicle	Present	Regionally restricted	3B	Expression is in the dorsal half.

3C ©

Specimen 3C: embryonic day 9.5; Otx1^tm1Asim/Otx1⁺, Otx2^tm1Pas/Otx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: optic vesicle	Weak	Uniform	3C

3D ©

3E ©

Specimen 3D,E: embryonic day 9.5; Otx1^tm1Asim/Otx1^tm1Asim, Otx2^tm1Pas/Otx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: optic vesicle	Weak	Uniform	3E , 3D

6A ©

Specimen 6A: embryonic day 10.5 (more

)
Note: Double labeled: blue - Otx2; brown - Pax2 (assay MGI:2137373).

Structure	Level	Pattern	Image	Note
TS17: optic cup	Present	Regionally restricted	6A	Expression is in the dorsal region.

6B ©

Specimen 6B: embryonic day 12.5 (more

)
Note: Double labeled: blue - Otx2; brown - Pax2 (assay MGI:2137373).

Structure	Level	Pattern	Image	Note
TS20: optic stalk	Absent		6B

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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