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Gene Expression Data
Assay Details
Assay
Reference: J:69847 Mahlapuu M, et al., Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations. Development. 2001 Jun;128(12):2397-406
Assay type: RNA in situ
MGI Accession ID: MGI:2135988
Gene symbol: Foxf1
Gene name: forkhead box F1
Probe: Foxf1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4 C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: left lung rudiment lobar bronchus mesenchyme Present Regionally restricted 4C Expression in subepithelial mesenchyme throughout the airways, the highest level is confined to mesenchyme surrounding the distal epithelium of the buds.
TS19: left lung rudiment mesenchyme Present Regionally restricted 4C Expression in subepithelial mesenchyme throughout the airways, the highest level is confined to mesenchyme surrounding the distal epithelium of the buds.
TS19: right lung rudiment mesenchyme Present Regionally restricted 4C Expression in subepithelial mesenchyme throughout the airways, the highest level is confined to mesenchyme surrounding the distal epithelium of the buds.
TS19: main bronchus mesenchyme Present Regionally restricted 4C Expression in subepithelial mesenchyme throughout the airways.
TS19: trachea mesenchyme Present Regionally restricted 4C Expression in subepithelial mesenchyme throughout the airways.

Specimen 5 A, B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: esophagus Present 5B , 5A
TS17: foregut Present 5B , 5A
TS17: hindgut Present 5B , 5A
TS17: left lung rudiment mesenchyme Present 5B , 5A
TS17: midgut Present 5B , 5A
TS17: oral region cavity Present 5B , 5A
TS17: right lung rudiment mesenchyme Present 5B , 5A
TS17: tail sclerotome Present 5B , 5A
TS17: trachea mesenchyme Present 5B , 5A
TS17: trunk sclerotome Present 5B , 5A
TS17: trunk mesenchyme Present 5B , 5A Expression in the splanchnic mesenchyme surrounding the foregut.

Specimen 5 C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: esophagus Present 5C
TS20: foregut Present 5C
TS20: hindgut Present 5C
TS20: left lung mesenchyme Present 5C
TS20: midgut Present 5C
TS20: oral cavity Present 5C
TS20: right lung mesenchyme Present 5C
TS20: tail sclerotome Present 5C
TS20: trachea mesenchyme Present 5C
TS20: trunk mesenchyme Present Regionally restricted 5C Expression in the splanchnic mesenchyme surrounding the foregut.

Specimen 5 D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung Present 5D

Specimen 5 E, F: embryonic day 10.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS17: hindgut Present 5E , 5F
TS17: midgut Present 5E , 5F
TS17: esophagus Absent 5E , 5F
TS17: foregut Absent 5E , 5F
TS17: left lung rudiment mesenchyme Absent 5E , 5F
TS17: lung Absent 5E , 5F
TS17: oral region cavity Absent 5E , 5F
TS17: right lung rudiment mesenchyme Absent 5E , 5F
TS17: tail sclerotome Absent 5E , 5F
TS17: trachea mesenchyme Absent 5E , 5F
TS17: trunk sclerotome Absent 5E , 5F
TS17: trunk mesenchyme Absent 5E , 5F Absence of expression in the splanchnic mesenchyme surrounding the foregut.

Specimen 5 G: embryonic day 12.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS20: hindgut Present 5G
TS20: midgut Present 5G
TS20: esophagus Absent 5G
TS20: foregut Absent 5G
TS20: left lung mesenchyme Absent 5G
TS20: lung Absent 5G
TS20: oral cavity Absent 5G
TS20: right lung mesenchyme Absent 5G
TS20: tail sclerotome Absent 5G
TS20: trachea mesenchyme Absent 5G
TS20: trunk mesenchyme Absent 5G Absence of expression in the splanchnic mesenchyme surrounding the foregut.

Specimen 5 H: embryonic day 12.5; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS20: lung Absent 5H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory