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Gene Expression Data
Assay Details
Assay
Reference: J:59338 Clouthier DE, et al., Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Dev Biol. 2000 Jan 1;217(1):10-24
Assay type: RNA in situ
MGI Accession ID: MGI:2135640
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Probe: lambda-mE1.3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1C +/+: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component mesenchyme Weak 1C +/+
TS15: 1st branchial arch mesenchyme Weak 1C +/+
TS15: 2nd branchial arch mesenchyme derived from neural crest Strong 1C +/+ Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4.
TS15: 3rd branchial arch mesenchyme derived from neural crest Strong 1C +/+ Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4.
TS15: branchial arch Strong Regionally restricted 1C +/+ Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4.
TS15: future hindbrain Strong Regionally restricted 1C +/+ Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4.
Specimen 1C -/-: embryonic day 9.0; Ednratm1Ywa/Ednratm1Ywa (more )
Structure Level Pattern Image Note
TS14: 1st branchial arch mandibular component mesenchyme Weak 1C -/- Expression in this mutant is the same as in wild-type embryos.
TS14: 1st branchial arch mesenchyme Weak 1C -/- Expression in this mutant is the same as in wild-type embryos.
TS14: 2nd branchial arch mesenchyme derived from neural crest Strong 1C -/- Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4 as in wild-type embryos.
TS14: 3rd branchial arch mesenchyme derived from neural crest Strong 1C -/- Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4 as in wild-type embryos.
TS14: branchial arch Strong Regionally restricted 1C -/- Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4 as in wild-type embryos.
TS14: future hindbrain Strong Regionally restricted 1C -/- Expression was strongly expressed in streams extending from the hindbrain into arches 2, 3, and 4 as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory