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Gene Expression Data
Assay Details
Assay
Reference: J:45301 Cygan JA, et al., Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development. 1997 Dec;124(24):5021-32
Assay type: RNA in situ
MGI Accession ID: MGI:1933279
Gene symbol: Wnt10b
Gene name: wingless-type MMTV integration site family, member 10B
Probe: Wnt10b cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3 B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb digit skin Present Regionally restricted 3B Diffuse expression in the epithelium of the digits.
TS22: hair follicle Present Regionally restricted 3B Expression on the dorsal surface of the autopod in the developing hair follicles.
Specimen 3 D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hand mesenchyme Present Regionally restricted 3D Expression on the ventral surface in the epithelium and mesenchyme of the developing footpads.
TS22: hand skin Present Regionally restricted 3D Expression on the ventral surface in the epithelium and mesenchyme of the developing footpads.
Specimen 3 F: embryonic day 14.5; En1tm1Alj/En1tm1Alj (more )
Structure Level Pattern Image Note
TS22: hand Present Regionally restricted 3F
Specimen 3 H: embryonic day 14.5; En1tm1Alj/En1tm1Alj (more )
Structure Level Pattern Image Note
TS22: forelimb digit 1 skin Present Regionally restricted 3H Ectopic expression in the proximal ventral epithelium.
TS22: forelimb digit 2 skin Present Regionally restricted 3H Ectopic expression in the proximal ventral epithelium.
TS22: forelimb digit 3 skin Present Regionally restricted 3H Ectopic expression in the proximal ventral epithelium.
TS22: forelimb digit 4 skin Present Regionally restricted 3H Ectopic expression in the proximal ventral epithelium.
Specimen 3 J: embryonic day 14.5; Wnt7atm1Amc/Wnt7atm1Amc (more )
Structure Level Pattern Image Note
TS22: forelimb digit 1 Absent 3J
TS22: forelimb digit 2 Absent 3J
TS22: forelimb digit 3 Absent 3J
TS22: forelimb digit 2 skin Absent 3J The normal expression of Wnt10b in the dorsal epithelium is absent.
TS22: forelimb digit 3 skin Absent 3J The normal expression of Wnt10b in the dorsal epithelium is absent.
TS22: hand Present Regionally restricted 3J A region of high expression at the base of digits 1-3. Expression in the developing ectopic footpads.
Specimen 3 L: embryonic day 14.5; En1tm1Alj/En1tm1Alj, Wnt7atm1Amc/Wnt7atm1Amc (more )
Structure Level Pattern Image Note
TS22: forelimb digit 1 Absent 3L
TS22: forelimb digit 2 Absent 3L
TS22: forelimb digit 3 Absent 3L
TS22: hand Present Regionally restricted 3L A region of high expression at the base of digits 1-3. Expression in the developing ectopic footpads.
TS22: forelimb digit 4 Present Regionally restricted 3L Expression is absent in part of digit 4.
Specimen 5 G: embryonic day 11.5; En1tm1Alj/En1tm1Alj (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present Regionally restricted 5G Expression in the endogenous AER and in a second distinct ridge of cells in the ventral ecoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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