Gene Expression Data
Assay Details
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Assay
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Reference:
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J:53903
Theil T, et al., Gli3 is required for Emx gene expression during dorsal telencephalon development. Development. 1999 Aug;126(16):3561-71
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1340418
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Gene symbol:
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Otx2
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Gene name:
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orthodenticle homeobox 2
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Probe:
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Otx2 cDNA1
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Probe preparation:
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Antisense RNA
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Assay notes:
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Xt<J>/Xt<J> embryos that were classified as exencephalic (based on overall brain morphology) were excluded from this study.
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Results
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Specimen
not shown:
embryonic day 8.5
(more  )
Specimen
not shown:
(close  )
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Genetic Background:
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involves: C3H * C57BL/6
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
not shown:
(close )
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Genetic Background:
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involves: C3H * C57BL/6
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Mutant Allele(s):
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Gli3Xt-J/Gli3Xt-J
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: future brain |
Present |
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Expression was within the correct expression domain at normal levels in the mutant.
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Specimen
not shown:
embryonic day 10.5
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: C3H * C57BL/6
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
not shown:
(close )
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Genetic Background:
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involves: C3H * C57BL/6
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Mutant Allele(s):
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Gli3Xt-J/Gli3Xt-J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: brain |
Present |
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Expression was within the correct expression domain at normal levels in the mutant.
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Specimen
4K:
embryonic day 11.5
(more )
Specimen
4K:
(close )
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Genetic Background:
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involves: C3H * C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4L:
(close )
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Genetic Background:
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involves: C3H * C57BL/6
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Mutant Allele(s):
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Gli3Xt-J/Gli3Xt-J
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: forebrain |
Present |
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4L
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Expression level was reduced in the forebrain.
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Analysis Tools