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Gene Expression Data
Assay Details
Assay
Reference: J:39344 Yoshikawa Y, et al., Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse. Dev Biol. 1997 Mar 15;183(2):234-42
Assay type: RNA in situ
MGI Accession ID: MGI:1338370
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Probe: Mash1 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: central nervous system Present 5A
TS15: peripheral nervous system Present 5A
TS15: embryo mesenchyme Absent 5A

Specimen 5B: embryonic day 9.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Structure Level Pattern Image Note
TS15: central nervous system Present 5B
TS15: peripheral nervous system Present 5B
TS15: embryo Present Regionally restricted 5B In Wnt3a-mutant embryos, ectopic expression is seen in an area ventral to the original neural tube, posterior to the forelimb.

Specimen 5C: embryonic day 9.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: Fig. 5C is anterior to the forelimb bud.
Structure Level Pattern Image Note
TS15: embryo Present 5C

Specimen 5D: embryonic day 9.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Note: Fig. 5D is posterior to the forelimb bud.
Structure Level Pattern Image Note
TS15: embryo Present Regionally restricted 5D Expression in the mutant is ectopically localized ventral to the original neural tube in the region posterior to the forelimbs.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory