Gene Expression Data
Assay Details
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Assay
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Reference:
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J:50582
Roebroek AJ, et al., Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development. 1998 Dec;125(24):4863-76
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1331444
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Gene symbol:
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Myl2
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Gene name:
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myosin, light polypeptide 2, regulatory, cardiac, slow
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Probe:
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Mylpc probe1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5L:
embryonic day 9.5
(more  )
Specimen
5L:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Age:
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embryonic day 9.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: heart |
Present |
Uniform |
5L
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Specimen
5M:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Furintm1Ajmr/Furintm1Ajmr
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: heart |
Present |
Uniform |
5M
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Expression marks two separate heart tubes in mutant.
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Specimen
6F:
embryonic day 9.5
(more )
Specimen
6F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Age:
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embryonic day 9.5
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Age Note:
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Theiler stage of this specimen assigned by curators from EMAGE.
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: heart |
Present |
Regionally restricted |
6F
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Expression is restricted to the ventricular and proximal outflow tracts.
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Specimen
6G:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Furintm1Ajmr/Furintm1Ajmr
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: heart |
Present |
Regionally restricted |
6G
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Normal levels of expression are detected, but mutant heart tubes are abnormally short and bifid.
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Analysis Tools