Gene Expression Data
Assay Details
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Assay
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Reference:
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J:48372
Tang SJ, et al., The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development. Development. 1998 May;125(10):1877-87
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1316853
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Gene symbol:
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T
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Gene name:
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brachyury, T-box transcription factor T
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Probe:
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T cDNA9
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
6a +/+:
embryonic day 7.0
(more  )
Specimen
6a +/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
6b +/+:
embryonic day 7.5
(more )
Specimen
6b +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
6c +/+:
embryonic day 8.5
(more )
Specimen
6c +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
6a -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Tlx2tm1Ut/Tlx2tm1Ut
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: embryo |
Present |
Regionally restricted |
6a -/-
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Expression is restricted to the posterior end.
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Specimen
6b -/- upper:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Tlx2tm1Ut/Tlx2tm1Ut
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo |
Present |
Regionally restricted |
6b -/- upper
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Expression is restricted to the posterior end.
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Specimen
6b -/- lower:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Tlx2tm1Ut/Tlx2tm1Ut
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo mesoderm |
Present |
Regionally restricted |
6b -/- lower
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In mutants with spherical morphology, the expression is mainly restricted to the presumptive mesoderm in one side of the embryo, presumably marking the posterior end.
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Specimen
6c -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Tlx2tm1Ut/Tlx2tm1Ut
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo |
Present |
Regionally restricted |
6c -/-
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In this spherical mutant, the expression is mainly restricted to one side of the embryo.
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| TS13: notochord |
Absent |
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6c -/-
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Specimen
6d:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * CD-1
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Mutant Allele(s):
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Tlx2tm1Ut/Tlx2tm1Ut
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo |
Present |
Regionally restricted |
6d
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Expression is restricted to one side of the embryo.
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| TS13: notochord |
Absent |
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6d
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Analysis Tools