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Gene Expression Data
Assay Details
Assay
Reference: J:30828 Ang SL, et al., A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development. 1996 Jan;122(1):243-52
Assay type: RNA in situ
MGI Accession ID: MGI:1275988
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: T cDNA9
Probe preparation: RNA
Results
Specimen 4E: embryonic day 7.75 (more )
Structure Level Pattern Image Note
TS11: node Present 4E
TS11: notochordal process Present 4E
TS11: primitive streak Present 4E

Specimen 4F: embryonic day 7.75; Otx2tm1Sla/Otx2tm1Sla (more )
Note: mutant embryo type 2
Structure Level Pattern Image Note
TS11: node Present 4F Expression is expanded in the primitive streak, in the node, and in a few headprocess cells extending anteriorly from the node.
TS11: notochordal process Present 4F Expression is expanded in the primitive streak, in the node, and in a few headprocess cells extending anteriorly from the node.
TS11: primitive streak Present 4F Expression is expanded in the primitive streak, in the node, and in a few headprocess cells extending anteriorly from the node.

Specimen not shown: embryonic day 7.75; Otx2tm1Sla/Otx2tm1Sla (more )
Note: mutant embryo type 1
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted Expression was found only in the proximal region of some embryos.

Specimen 4M: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: notochord Present 4M
TS13: primitive streak Present 4M

Specimen 4N: embryonic day 8.5; Otx2tm1Sla/Otx2tm1Sla (more )
Note: mutant embryo type 2
Structure Level Pattern Image Note
TS13: embryo Present 4N Expression is present anteriorly but appeared to bud off and diverge from the axial notochord.
TS13: primitive streak Present 4N

Specimen 4O: embryonic day 8.5; Otx2tm1Sla/Otx2tm1Sla (more )
Note: mutant embryo type 1
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 4O Expression is detected in the primitive streak but is absent from the anterior midline.
TS13: primitive streak Present 4O


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory