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Myh11tm2(cre/ERT2)Zhji
Targeted Allele Detail
Summary
Symbol: Myh11tm2(cre/ERT2)Zhji
Name: myosin, heavy polypeptide 11, smooth muscle; targeted mutation 2, Jiliang Zhou
MGI ID: MGI:8262980
Synonyms: Myh11Cre
Gene: Myh11  Location: Chr16:14012392-14109227 bp, - strand  Genetic Position: Chr16, 9.71 cM
Alliance: Myh11tm2(cre/ERT2)Zhji page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:366242
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Myh11tm2(cre/ERT2)Zhji expression driven by 1 gene
 
Mutation details: An NLS-cre/ERT2-polyA cassette was inserted immediately after the start codon via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:366242)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myh11 (mouse)
Summary of all recombinase alleles driven by Myh11.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myh11 Mutation:  96 strains or lines available
References
Original:  J:366242 Dong K, et al., Generation of a novel constitutive smooth muscle cell-specific Myh11-driven Cre mouse model. J Mol Cell Cardiol. 2025 May;202:144-152
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory