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Gm38411em1(icre,CD2)Cln
Endonuclease-mediated Allele Detail
Summary
Symbol: Gm38411em1(icre,CD2)Cln
Name: predicted gene, 38411; endonuclease-mediated mutation 1, Marco Colonna
MGI ID: MGI:8223567
Synonyms: Gm38411iCre-hCD2
Gene: Gm38411  Location: Chr3:94272842-94278330 bp, - strand  Genetic Position: Chr3, Syntenic
Alliance: Gm38411em1(icre,CD2)Cln page
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Gm38411em1(icre,CD2)Cln expression driven by 1 gene
 
Mutation detailsSequence coding for codon improved Cre recombinase, self-cleaving oligopeptide P2A and human CD2, plus polyA signal sequence, was inserted into an intron of ENSMUSG00000104669 or exon of XR_867461. (J:369928)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gm38411 (mouse)
Summary of all recombinase alleles driven by Gm38411.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gm38411 Mutation:  0 strains or lines available
References
Original:  J:369928 Rodrigues PF, et al., Rorgammat-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens. Cell. 2025 May 15;188(10):2720-2737.e22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/29/2025
MGI 6.24
The Jackson Laboratory