Tbr1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:360776 Di Michele M, et al., E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8188168
Gene symbol:	Tbr1
Gene name:	T-box brain transcription factor 1

Antibody:

Results

2D TBR1 CTL ©

Specimen 2D TBR1 CTL: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: brain	Present		2D TBR1 CTL

2D TBR1 KO ©

Specimen 2D TBR1 KO: embryonic day 14.5; E4f1^tm1.1Llca/E4f1^tm1.1Llca, Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: brain	Present	Regionally restricted	2D TBR1 KO	Authors report a decreased number of expressing cells compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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