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Gene Expression Data
Assay Details
Assay
Reference: J:110322 Lamprianou S, et al., Receptor protein tyrosine phosphatase gamma is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal development. Mol Cell Biol. 2006 Jul;26(13):5106-19
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7863532
Gene symbol: Ptprg
Gene name: protein tyrosine phosphatase receptor type G
Reporter: Beta-geo
Direct Detection
Results
Specimen 2A E14.5: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: brain Present 2A E14.5 lower The patterns of expression appeared identical with that of the RNA in situ hybridization.
Specimen 2A P2: postnatal day 2; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS27: brain Present 2A P2 lower The patterns of expression appeared identical with that of the RNA in situ hybridization.
Specimen 2B E10.5: embryonic day 10.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS17: brain vascular element Present 2B E10.5
TS17: nose Present 2B E10.5
TS17: somite Present 2B E10.5
TS17: limb bud Strong 2B E10.5
TS17: midbrain-hindbrain junction Strong 2B E10.5
Specimen 2B E12.5: embryonic day 12.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS20: brain vascular element Present 2B E12.5
TS20: forelimb Present 2B E12.5
TS20: nose Present 2B E12.5
TS20: midbrain-hindbrain junction Strong 2B E12.5
Specimen 2C E14.5 upper: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present 2C E14.5 upper
Specimen 2C E14.5 lower: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: diencephalon Present 2C E14.5 lower
TS22: midbrain Present 2C E14.5 lower
TS22: dorsal root ganglion Strong 2C E14.5 lower
Specimen 2C E17.5 upper: embryonic day 17.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS25: inferior glossopharyngeal ganglion Present 2C E17.5 upper
TS25: trigeminal ganglion Present 2C E17.5 upper
Specimen 2C E17.5 lower: embryonic day 17.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS25: diencephalon Present 2C E17.5 lower
TS25: midbrain Present 2C E17.5 lower
Specimen 2D upper: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2D upper
TS28: hippocampus CA1 Present 2D upper
TS28: hippocampus CA2 Present 2D upper
TS28: hippocampus CA3 Present 2D upper
TS28: cerebral cortex subventricular zone Absent 2D upper
TS28: corpus striatum Absent 2D upper
Specimen 2D lower: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2D lower
TS28: hypothalamus Present 2D lower
TS28: thalamus Present 2D lower
TS28: cerebral cortex subventricular zone Absent 2D lower
TS28: corpus striatum Absent 2D lower
Specimen 2E P2: postnatal day 2; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS27: spinal cord dorsal horn Present 2E_P2
TS27: spinal cord ventral horn Present 2E_P2
Specimen 2E Adult Dorsal: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: spinal cord dorsal horn Present 2E_Adult Dorsal
Specimen 2E Adult Ventral: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: spinal cord ventral horn Absent 2E_Adult Ventral
Specimen 2E Adult right: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: spinal cord dorsal horn Present 2E_right
Specimen 3A: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Note: Double labeled: blue - Ptprg reporter; green - Rbfox3 (assay MGI:7863537).
Structure Cell Type Level Pattern Image Note
TS28: hippocampus CA1 hippocampal neuron Strong 3A beta-gal left , 3A upper Coexpressed with NeuN/Rbfox3.
TS28: hippocampus CA2 hippocampal neuron Strong 3A beta-gal left , 3A upper Coexpressed with NeuN/Rbfox3.
TS28: hippocampus CA3 hippocampal neuron Strong 3A beta-gal left , 3A upper Coexpressed with NeuN/Rbfox3.
TS28: piriform cortex neuron of the forebrain Strong 3A merge , 3A beta-gal right Coexpressed with NeuN/Rbfox3.
Specimen 3B: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Cell Type Level Pattern Image Note
TS28: hippocampus CA1 hippocampal neuron Strong 3B upper The expression corresponded closely to staining with cresyl violet, which labels the Nissl bodies of neurons.
TS28: hippocampus CA2 hippocampal neuron Strong 3B upper The expression corresponded closely to staining with cresyl violet, which labels the Nissl bodies of neurons.
TS28: hippocampus CA3 hippocampal neuron Strong 3B upper The expression corresponded closely to staining with cresyl violet, which labels the Nissl bodies of neurons.
Specimen 4A Layer II upper: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present 4A Layer II 87.1% of the BrdU-positive cells also contained beta-Gal.
Specimen 4A Layer V: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: cortical layer V Present Graded 4A Layer V 93% of the BrdU-positive cells were positive for beta-Gal, with a decreasing anterior-posterior gradient.
Specimen 4A Layer II lower: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: cortical layer II Present Graded 4A lower Expressed in a anterior-posterior increasing gradient.
Specimen 4B Layer II: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Cell Type Level Pattern Image Note
TS28: cortical layer II pyramidal neuron Present 4B Layer II Expressed in neutral red stained pyramidal neurons.
Specimen 4B Layer V: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Cell Type Level Pattern Image Note
TS28: cortical layer V pyramidal neuron Present 4B Layer IV Expressed in neutral red stained pyramidal neurons.
Specimen 5 Olfactory bulb: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: main olfactory bulb layer Strong Regionally restricted 5_Olfactory bulb Expressed in the glomerular layer.
Specimen 5 Eye: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: eye epithelium Strong 5_Eye
Specimen 5 Tongue: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: tongue epithelium Strong 5_Tongue
Specimen 5 Ear: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: ear epithelium Strong 5_Ear
Specimen 5 Cranial Nerves 1: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: olfactory nerve Present 5_Cranial Nerves 1
Specimen 5 Cranial Nerves 2: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: olfactory nerve Present 5_Cranial Nerves 2
Specimen 5 Cranial Nerves 3: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: oculomotor nerve Present 5_Cranial Nerves 3
Specimen 5 Cranial Nerves 4: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: facial nerve Present 5_Cranial Nerves 4
TS22: trigeminal nerve Present 5_Cranial Nerves 4
Specimen 5 Cranial Nerves 5: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: trigeminal nerve Present 5_Cranial Nerves 5
TS22: vagus nerve Present 5_Cranial Nerves 5
TS22: vestibulocochlear nerve Present 5_Cranial Nerves 5
Specimen 5 Cranial Nerves 6: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: glossopharyngeal nerve Present 5_Cranial Nerves 6
TS22: trigeminal nerve Present 5_Cranial Nerves 6
TS22: vagus nerve Present 5_Cranial Nerves 6
Specimen 5 Nasal cavity: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: nasal cavity Strong 5_Nasal cavity
Specimen 5 Vibrissae: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: vibrissa follicle Strong 5_Vibrissae
Specimen not shown: embryonic day 10.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS17: neural tube Absent
Specimen not shown: embryonic day 12.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS20: spinal cord Absent
Specimen not shown: embryonic day 14.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS22: inferior glossopharyngeal ganglion Present
TS22: medulla oblongata Present
TS22: pons Present
TS22: trigeminal ganglion Present
Specimen not shown: embryonic day 17.5; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS25: medulla oblongata Present
TS25: pons Present
TS25: dorsal root ganglion Strong
Specimen not shown: postnatal adult; Ptprgtm1Shar/Ptprg+ (more )
Structure Level Pattern Image Note
TS28: corpus callosum Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/06/2026
MGI 6.29 		The Jackson Laboratory