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Gene Expression Data
Assay Details
Assay
Reference: J:354443 Zhang B, et al., SMC3 contributes to heart development by regulating super-enhancer associated genes. Exp Mol Med. 2024 Aug;56(8):1826-1842
Assay type: RNA in situ
MGI Accession ID: MGI:7861270
Gene symbol: Smc3
Gene name: structural maintenance of chromosomes 3
Probe: Mm-Smc3 (1121291)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope probe. Amplification channel C1.
Results
Specimen 1a E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present Widespread 1a E10.5 WT DAPI;Smc3 , 1a E10.5 WT Smc3
Specimen 1a P0 WT: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: heart Present Widespread 1a P0 WT DAPI;Smc3 , 1a P0 WT Smc3
Specimen 6a Smc3fl/fl: embryonic day 10.5; Smc3em1Smoc/Smc3em1Smoc (more )
Note: Double labeled: orange - Smc3; red - Ets2 (assay MGI:7861276).
Structure Level Pattern Image Note
TS17: heart Present 6a Smc3fl/fl i , 6a Smc3fl/fl top , 6a Smc3fl/fl ii
Specimen 6a Smc3fl/fl; Nkx2.5-Cre: embryonic day 10.5; Nkx2-5em2(icre)Gpt/Nkx2-5+, Smc3em1Smoc/Smc3em1Smoc (more )
Note: Conditional mutant. Double labeled: orange - Smc3; red - Ets2 (assay MGI:7861276).
Structure Level Pattern Image Note
TS17: heart Ambiguous 6a Smc3fl/fl;Nkx2.5-Cre ii , 6a Smc3fl/fl;Nkx2.5-Cre top , 6a Smc3fl/fl;Nkx2.5-Cre i
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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