Gene Expression Data
Assay Details
Assay
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Reference:
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J:243177
Lania G, et al., TBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ Cells. PLoS One. 2015;10(9):e0138525
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7859262
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Gene symbol:
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Kdr
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Gene name:
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kinase insert domain protein receptor
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Probe:
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Vegfr2 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
6A:
embryonic day 9.5
(more )
Note: 22 somite stage embryo.
Specimen
6A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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22 somite stage embryo.
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Structure |
Level |
Pattern |
Image |
Note |
TS15: secondary heart field |
Present |
Regionally restricted |
6A
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Expression is in the in the mesodermal/epithelial-like tissue of the posterior second heart field in the proximity of the cardiac inflow tract and in the dorsal mesenchyme protrusion region.
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TS15: blood vessel |
Present |
Regionally restricted |
6A
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Expression is in the endothelium.
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Specimen
6A':
(close )
Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1tm1Bld
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
22 somite stage embryo.
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: secondary heart field |
Present |
Regionally restricted |
6A'
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The expression domains in this mutant had expanded more dorsally and anteriorly compared to wild-type.
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Specimen
7A':
embryonic day 8.5
(more )
Note: 7 somite stage embryo.
Specimen
7A':
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Cryosection
|
Note:
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7 somite stage embryo.
|
Specimen
7B':
embryonic day 8.5
(more )
Note: 7 somite stage embryo.
Specimen
7B':
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
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Cryosection
|
Note:
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7 somite stage embryo.
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Specimen
7C':
embryonic day 8.5
(more )
Note: 7 somite stage embryo.
Specimen
7C':
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
|
Sex:
|
Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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7 somite stage embryo.
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Specimen
7D':
embryonic day 8.5
(more )
Note: 7 somite stage embryo.
Specimen
7D':
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
|
Sex:
|
Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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7 somite stage embryo.
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