Tbr1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:275567 Zurkirchen L, et al., Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019 May 16;10(1):2192
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7856695
Gene symbol:	Tbr1
Gene name:	T-box brain transcription factor 1

Antibody:	anti-Tbr1 (AB31940)
Detection system:	Secondary antibody

Results

S2d Control ©

Specimen S2d Control Tbr1: embryonic day 18.5 (more

)
Note: The following genotypes were used as controls: Yy1lx/lx, Emx1-Cre Yy1wt/wt, Emx1-Cre Yy1lx/wt. Double labeled: red - Tbr1; green - Reln (assay MGI:7856694).

Structure	Cell Type	Level	Pattern	Image	Note
TS26: neocortex	neuron	Present	Regionally restricted	S2d Control	Expression in neurons in layers V/VI.

S2d Yy1cKO ©

Specimen S2d Yy1cKO Tbr1: embryonic day 18.5; Emx1^tm1(cre)Krj/Emx1⁺, Yy1^tm2.1Yshi/Yy1^tm2.1Yshi (more

)
Note: Conditional mutant. Double labeled: red - Tbr1; green - Reln (assay MGI:7856694).

Structure	Cell Type	Level	Pattern	Image	Note
TS26: neocortex	neuron	Weak		S2d Yy1cKO	Number of expressing neurons decreased compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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