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Gene Expression Data
Assay Details
Assay
Reference: J:175804 Brzezinski JA 4th, et al., Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina. Development. 2011 Aug;138(16):3519-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855850
Gene symbol: Olig2
Gene name: oligodendrocyte transcription factor 2
Results
Specimen 1H/J/K/L: embryonic day 14.5; Ascl1tm1Reed/Ascl1+ (more )
Note: Triple labeled: white - Olig2; green - Ascl1 reporter (assay MGI:7855848); red - Neurog2 (assay MGI:7855849).
Structure Level Pattern Image Note
TS22: retina Present 1K , 1H , 1L , 1J Cells that expressed Ascl1-GFP only; Olig2 only; Neurog2 only; Ascl1-GFP and Olig2; Ascl1-GFP and Neurog2; Olig2 and Neurog2; and all three transcription factors were observed.
Specimen 1M: embryonic day 14.5; Ascl1tm1Reed/Ascl1tm1Reed (more )
Note: Triple labeled: white - Olig2; green - Ascl1 reporter (assay MGI:7855848); red - Neurog2 (assay MGI:7855849).
Structure Level Pattern Image Note
TS22: retina Present 1M Similar as in the control.
Specimen S1C/D: embryonic day 18.5; Ascl1tm1Reed/Ascl1+ (more )
Note: Triple labeled: white - Olig2; green - Ascl1 reporter (assay MGI:7855848); red - Neurog2 (assay MGI:7855849).
Structure Level Pattern Image Note
TS26: retina Present S1D , S1C Cells that expressed Ascl1-GFP only; Olig2 only; Neurog2 only; Ascl1-GFP and Olig2; Ascl1-GFP and Neurog2; Olig2 and Neurog2; and all three transcription factors were observed.
Specimen S1G/H: embryonic day 18.5; Ascl1tm1Reed/Ascl1tm1Reed (more )
Note: Triple labeled: white - Olig2; green - Ascl1 reporter (assay MGI:7855848); red - Neurog2 (assay MGI:7855849).
Structure Level Pattern Image Note
TS26: retina Present S1G , S1H Mutant animals had each population as in the control, but there were fewer Ascl1-GFP+, Neurog2+ and Olig2+ cells seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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