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Gene Expression Data
Assay Details
Assay
Reference: J:294282 Li L, et al., The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855693
Gene symbol: Pax6
Gene name: paired box 6
Results
Specimen S2D Pax6 Control: embryonic day 12.5; Tg(Dach1-cre)1Krs/0 (more )
Structure Cell Type Level Pattern Image Note
TS20: neocortex radial glial cell Present S2D Pax6 Control lower , S2D Pax6 Control
Specimen S2D Pax6 cKO: embryonic day 12.5; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: neocortex Present S2D Pax6 cKO , S2D Pax6 cKO lower Expression unaffected compared to control.
Specimen 3A Pax6 Control: embryonic day 14.5; Tg(Dach1-cre)1Krs/0 (more )
Structure Cell Type Level Pattern Image Note
TS22: neocortex radial glial cell Present 3A Control lower , 3A Control
Specimen 3A Pax6 cKO: embryonic day 14.5; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: neocortex Weak 3A cKO , 3A cKO lower Expression decreased compared to control.
Specimen 3D Pax6 Control: embryonic day 16.5; Tg(Dach1-cre)1Krs/0 (more )
Structure Cell Type Level Pattern Image Note
TS24: neocortex radial glial cell Present 3D Pax6 Control , 3D Pax6 Control lower
Specimen 3D Pax6 cKO: embryonic day 16.5; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: neocortex Weak 3D Pax6 cKO lower , 3D Pax6 cKO Expression signficantly decreased compared to control.
Specimen 4H Pax6 Control: embryonic day 17.5; Tg(Dach1-cre)1Krs/0 (more )
Note: Double labeled: green - Pax6; red - EdU.
Structure Level Pattern Image Note
TS25: neocortex Present 4H Pax6 Control right , 4H Pax6 Control
Specimen 4H Pax6 cKO: embryonic day 17.5; Ash2ltm1.1Bcgen/Ash2ltm1.1Bcgen, Tg(Dach1-cre)1Krs/0 (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - EdU.
Structure Level Pattern Image Note
TS25: neocortex Present 4H Pax6 cKO , 4H Pax6 cKO right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory