About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:161201 Gao N, et al., Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7855369
Gene symbol: Cdx2
Gene name: caudal type homeobox 2
Antibody: anti-CDX2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Control embryos were derived from matings between Cdx2loxP/+ VillinCre+ male mice and Cdx2loxP/loxP female mice.
Results
Specimen S1a Control: embryonic day 14.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: intestine epithelium Present S1a Control
Specimen S1a Mutant: embryonic day 14.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: intestine epithelium Present S1a Mutant
Specimen S1b Control: embryonic day 15.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: intestine epithelium Present S1b Control
Specimen S1b Mutant: embryonic day 15.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: intestine epithelium Weak Regionally restricted S1b Mutant Depletion of expression from intestinal epithelial cell nuclei initiated around E15.5.
Specimen S1c Control duo.: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: duodenum epithelium Present S1c Control duo.
Specimen S1c Mutant duo.: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: duodenum epithelium Trace Regionally restricted S1c Mutant duo. tDepletion of expression reached 85-95% of epithelial cells by E18.5.
Specimen S1c Control ile.: embryonic day 18.5; Cdx2tm1Khk/?, Tg(Vil1-cre)997Gum/? (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ileum epithelium Present S1c Control ile.
Specimen S1c Mutant ile.: embryonic day 18.5; Cdx2tm1Khk/Cdx2tm1Khk, Tg(Vil1-cre)997Gum/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ileum epithelium Trace Regionally restricted S1c Mutant ile. Depletion of expression reached 85-95% of epithelial cells by E18.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory