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Gene Expression Data
Assay Details
Assay
Reference: J:174826 Rousselet E, et al., PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. J Lipid Res. 2011 Jul;52(7):1383-91
Assay type: Western blot
MGI Accession ID: MGI:7850849
Gene symbol: Ldlr
Gene name: low density lipoprotein receptor
Antibody: Anti-LDLR
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Liver WT P adult TS28: liver Present C57BL/6J Not Specified
Liver Ldlr-/- P adult TS28: liver Absent B6.129S7-Ldlrtm1Her/J Ldlrtm1Her/Ldlrtm1HerNot Specified
WT 1 P adult TS28: main olfactory bulb Present C57BL/6J Not Specified
WT 2 P adult TS28: main olfactory bulb Present C57BL/6J Not Specified
WT 3 P adult TS28: main olfactory bulb Present C57BL/6J Not Specified
WT 4 P adult TS28: main olfactory bulb Present C57BL/6J Not Specified
Pcsk9-/- 1 P adult TS28: main olfactory bulb Present (a) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Pcsk9-/- 2 P adult TS28: main olfactory bulb Present (a) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Pcsk9-/- 3 P adult TS28: main olfactory bulb Present (a) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Pcsk9-/- 4 P adult TS28: main olfactory bulb Present (a) B6.129(Cg)-Pcsk9tm1.2Prat Pcsk9tm1.2Prat/Pcsk9tm1.2PratNot Specified
Notes:
(a) Similar as the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory