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Gene Expression Data
Assay Details
Assay
Reference: J:283318 Ruan QT, et al., A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins. J Neurosci. 2020 Jan 2;40(1):107-130
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7840443
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH (H196, sc-14007)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 15B WT: postnatal adult (more )
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 15B WT
TS28: ventral tegmental area Present 15B WT
Specimen 15B H1+/-: postnatal adult; Hnrnph1em1Lagbu/Hnrnph1+ (more )
Structure Level Pattern Image Note
TS28: substantia nigra pars compacta Present 15B +/- Similar as in the wild-type.
TS28: ventral tegmental area Present 15B +/- Similar as in the wild-type.
Specimen 16A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal striatum Present 16A
Specimen 16B: postnatal adult; Hnrnph1em1Lagbu/Hnrnph1+ (more )
Structure Level Pattern Image Note
TS28: dorsal striatum Present 16B Similar as in the wild-type.
Specimen 16D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ventral striatum Present 16D
Specimen 16E: postnatal adult; Hnrnph1em1Lagbu/Hnrnph1+ (more )
Structure Level Pattern Image Note
TS28: ventral striatum Present 16E A small, but statistically significant increase in optical density was observed.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory