About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:171050 Thiagarajan RD, et al., Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
Assay type: RNA in situ
MGI Accession ID: MGI:7840378
Gene symbol: Fbp1
Gene name: fructose bisphosphatase 1
Probe: RIKEN clone C730030M09 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Authors described this gene as an 'anchor gene', which was defined as "genes whose expression is absolutely specific to a given anatomical compartment and/or developmental stage" in mouse kidney development.
Results
Specimen 5B': embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical early proximal tubule Present 5B' Fbp1 Section in situ hybridization confirmed specific expression in early proximal tubule. Validated anchor gene. Expression was restricted to stage IV tubules.
Specimen S2: postnatal adult (more )
Structure Level Pattern Image Note
TS28: proximal straight tubule Present S2_Fbp1 top , S2a
TS28: segment 2 of proximal tubule Present S2e , S2_Fbp1 top
TS28: segment 1 of proximal tubule Present Regionally restricted S2e , S2_Fbp1 top Expression was absent from the first portion of segment 1 adjacent to the renal corpuscle, but present in other segment 1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory