Hcn4 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:355648 Abassah-Oppong S, et al., A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival. Nat Commun. 2024 Oct 10;15(1):8793
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7834450
Gene symbol:	Hcn4
Gene name:	hyperpolarization-activated, cyclic nucleotide-gated K+ 4

Antibody:	anti-HCN4 (MA3-903)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

4C WT HCN4 ©

4C WT Merge ©

Specimen 4C WT: embryonic day 11.5 (more

)
Note: Triple labeled: red - Hcn4; blue - Nkx2-5 (assay MGI:7834453); green - Shox2 (assay MGI:7834405).

Structure	Level	Pattern	Image	Note
TS19: sinoatrial node	Present		4C WT HCN4 , 4C WT merge boxed , 4C WT Merge

Specimen 4C GD^delta/delta: embryonic day 11.5; Del(3Rr805-Rr776)2Lap/Del(3Rr805-Rr776)2Lap (more

)
Note: Triple labeled: red - Hcn4; blue - Nkx2-5 (assay MGI:7834453); green - Shox2 (assay MGI:7834405).

Structure	Level	Pattern	Image	Note
TS19: sinoatrial node	Present		4C GD^delta/delta HCN4 , 4C GD^delta/delta merge boxed , 4C GD^delta/delta Merge

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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