Del(3Rr805-Rr776)2Lap
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(3Rr805-Rr776)2Lap
• Name: deletion, Chr 3, Len A Pennacchio 2
• MGI ID: MGI:7797741
• Synonyms: Del(3mm1849-mm2112), GD^delta
• Gene: Del(3Rr805-Rr776)2Lap Location: unknown Genetic Position: Chr3, Syntenic

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intergenic deletion
• Del(3Rr805-Rr776)2Lap involves 9 genes/genome features (Gm35184, Gm35236, Gm66478 ...) View all
• CRISPR-targeting deleted the 582 kb of the gene dessert downstream of Shox2. (J:355648)

Expression

In Mice Carrying this Mutation:

36 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(3Rr805-Rr776)2Lap Mutation: 0 strains or lines available

References

• Original: J:355648 Abassah-Oppong S, et al., A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival. Nat Commun. 2024 Oct 10;15(1):8793
• All: 1 reference(s)