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Gene Expression Data
Assay Details
Assay
Reference: J:353600 Liu X, et al., Dynamic regulation of alternative polyadenylation by PQBP1 during neurogenesis. Cell Rep. 2024 Aug 27;43(8):114525
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7797913
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: Anti-Ki67 (ab15580)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5I Control: embryonic day 14.5 (more )
Note: Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS22: brain Present Regionally restricted 5I Control Ki67/BrdU double staining enabled the distinction between progenitors that exited the cell cycle (Ki67-&BrdU+) and proliferating progenitors (Ki67+&BrdU+).
Specimen 5I Pqbp1W215X: embryonic day 14.5; Pqbp1em1Jhhan/Pqbp1em1Jhhan (more )
Note: Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS22: brain Present Regionally restricted 5I Pqbp1W215X A significant increase in the proportion of differentiated and non-proliferating progenitors were observed in Pqbp1<W215X> embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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