Tg(Kap-AGT)1827/1Sig
Transgene Detail
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| Symbol: |
Tg(Kap-AGT)1827/1Sig |
| Name: |
transgene insertion 1827/1, Curt Sigmund |
| MGI ID: |
MGI:3793473 |
| Synonyms: |
KAP-hAGT |
| Transgene: |
Tg(Kap-AGT)1827/1Sig Location: unknown
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| Alliance: |
Tg(Kap-AGT)1827/1Sig page
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| Strain of Origin: |
(C57BL/6J x SJL/J)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Kap-AGT)1827/1Sig expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
AGT (183) |
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Mutation details: The transgene construct consists of 1542 bp of the murine Kap promoter fused to the coding region of the human AGT gene. Expression of transgenic mRNA is evident in kidney, but not in liver, heart, lung, brain, adipose tissue, submandibular gland, spleen, muscle, adrenal gland, or vascular tissue. In addition to line 1827/1, line 1848/3 was also produced.
(J:83177)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:83177 Ding Y, et al., The kidney androgen-regulated protein promoter confers renal proximal tubule cell-specific and highly androgen-responsive expression on the human angiotensinogen gene in transgenic mice. J Biol Chem. 1997 Oct 31;272(44):28142-8 |
| All: |
4 reference(s) |
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Analysis Tools
