About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:305429 Kaiser M, et al., Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse. Development. 2021 Apr 15;148(8):dev195651
Assay type: RNA in situ
MGI Accession ID: MGI:7788367
Gene symbol: Nhlh2
Gene name: nescient helix loop helix 2
Probe: Nhlh2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5D control: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: neural tube neuroblast (sensu Vertebrata) Present 5D control Nhlh2
TS17: otocyst neuroblast (sensu Vertebrata) Present 5D control Nhlh2
Specimen 5D Tbx2/3cDKO: embryonic day 10.5; Tbx2tm2.1Vmc/Tbx2tm2.1Vmc, Tbx3tm1Pa/Tbx3tm1Pa, Tg(Pax2-cre)10Shwl/0, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: neural tube neuroblast (sensu Vertebrata) Present 5D Tbx2/3cDKO Nhlh2 Expression in neuroblasts was unaffected in the Tbx2/3cDKO.
TS17: otocyst neuroblast (sensu Vertebrata) Present 5D Tbx2/3cDKO Nhlh2 Expression in neuroblasts was unaffected in the Tbx2/3cDKO.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory