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Gene Expression Data
Assay Details
Assay
Reference: J:173619 Barron F, et al., Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis. Development. 2011 Jun;138(11):2249-59
Assay type: RNA in situ
MGI Accession ID: MGI:7782469
Gene symbol: Dlx6
Gene name: distal-less homeobox 6
Probe: Dlx6 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6C: embryonic day 9.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Widespread 6C
TS15: 2nd branchial arch Present 6C
Specimen 6D: embryonic day 9.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Widespread 6D
TS15: 2nd branchial arch Present 6D
Specimen not shown: embryonic day 10.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Present Regionally restricted Expression was downregulated in the distal and oral aspects.
Specimen not shown: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch Present Widespread Expression was present throughout the mandibular arch.
Specimen not shown: embryonic day 11.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present Regionally restricted Expression was downregulated in the distal and oral aspects corresponding to the lateral lingual swelling.
Specimen not shown: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: 1st branchial arch Present Widespread Expression continued in the disto-oral region.
Specimen not shown: embryonic day 12.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Structure Level Pattern Image Note
TS20: tongue Present
TS20: jaw Present Regionally restricted Expressed in the proximal jaw.
Specimen not shown: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: jaw Present Regionally restricted Expressed only in the proximal jaw, owing to the absence of the tongue.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory