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Gene Expression Data
Assay Details
Assay
Reference: J:122300 Taoudi S, et al., Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9399-403
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7767923
Gene symbol: Ptprc
Gene name: protein tyrosine phosphatase receptor type C
Antibody: anti-CD45
Detection system: alkaline phosphatase
Results
Specimen 3B/C/E: embryonic day 11.5 (more )
Note: Double labeled: green - Ptprc; red - Pecam1 (assay MGI:7767922).
Structure Cell Type Level Pattern Image Note
TS19: blood AGM hematopoietic stem cell Present 3C , 3B , 3E Coexpressed with Pecam1 in cells localized predominantly to the luminal surface of the endothelial lining of the dorsal aorta, and usually incorporated within intraaortic clusters with occasional integration into the endothelial layer.

Specimen 4A/C: embryonic day 11.5 (more )
Note: Luminal view. Double labeled: green - Ptprc; red - Pecam1 (assay MGI:7767922).
Structure Cell Type Level Pattern Image Note
TS19: blood AGM hematopoietic stem cell Present 4C , 4A Coexpressed with Pecam1 in cells scattered on the floor but not in subendothelial mesenchymal layers of the dorsal aorta.

Specimen 4B: embryonic day 11.5 (more )
Note: Subluminal view. Double labeled: green - Ptprc; red - Pecam1 (assay MGI:7767922).
Structure Cell Type Level Pattern Image Note
TS19: blood AGM hematopoietic stem cell Present 4B Coexpressed with Pecam1 in cells scattered on the floor but not in subendothelial mesenchymal layers of the dorsal aorta.

Specimen 5G: embryonic day 11.5 (more )
Note: Double labeled: green - Ptprc; red - Pecam1 (assay MGI:7767922).
Structure Cell Type Level Pattern Image Note
TS19: blood AGM hematopoietic stem cell Present 5G Expressed in the dorsal and ventral domains of the dorsal aorta.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory