Gene Expression Data
Assay Details
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Assay
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Reference:
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J:181926
Jo HS, et al., Pten coordinates retinal neurogenesis by regulating Notch signalling. EMBO J. 2012 Feb 15;31(4):817-28
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7764457
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Gene symbol:
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Sox9
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Gene name:
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SRY (sex determining region Y)-box 9
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Antibody:
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anti-Sox9
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Detection system:
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Secondary antibody coupled to Cy3
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Results
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Specimen
3K Sox9 Pax6-aCre:
(close  )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Tg(Pax6-cre,GFP)2Pgr/0
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina |
Mueller cell |
Present |
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3K
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Expression in embryonic retinal progenitor cells, Muller glia precursors and Muller glia.
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| TS28: retina |
retinal progenitor cell |
Present |
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3K
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Expression in embryonic retinal progenitor cells, Muller glia precursors and Muller glia.
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Specimen
3L Sox9 Pten-cko:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Ptentm2Mak/Ptentm2Mak
Tg(Pax6-cre,GFP)2Pgr/0
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina |
Mueller cell |
Present |
Regionally restricted |
3L
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Authors report ~33% reduction in Muller glia and Muller glia precursors compared to control.
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Analysis Tools
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