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Gene Expression Data
Assay Details
Assay
Reference: J:181926 Jo HS, et al., Pten coordinates retinal neurogenesis by regulating Notch signalling. EMBO J. 2012 Feb 15;31(4):817-28
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7764449
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 2C Sox2 Pax6-aCre: postnatal day 4; Tg(Pax6-cre,GFP)2Pgr/0 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina retinal progenitor cell Present 2C Pax6-aCre
Specimen 2C Sox2 Pten-cko: postnatal day 4; Ptentm2Mak/Ptentm2Mak, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina retinal progenitor cell Present Regionally restricted 2C Pten-cko Number of retinal progenitor cells significantly reduced.
Specimen 6A Sox2 Pax6-aCre: postnatal day 4; Tg(Pax6-cre,GFP)2Pgr/0 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina retinal progenitor cell Present 6A Sox2 Pax6-aCre
Specimen 6A Sox2 Pten-cko: postnatal day 4; Ptentm2Mak/Ptentm2Mak, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina retinal progenitor cell Present Regionally restricted 6A Sox2 Pten-cko Number of retinal progenitor cells significantly reduced.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory