Tle3 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:74989 McEvilly RJ, et al., Transcriptional regulation of cortical neuron migration by POU domain factors. Science. 2002 Feb 22;295(5559):1528-32
Assay type:	RNA in situ
MGI Accession ID:	MGI:7751261
Gene symbol:	Tle3
Gene name:	transducin-like enhancer of split 3

Probe:

TLE3 probe

Results

Specimen 3A TLE3 WT: postnatal day 0 (more

)

Structure	Level	Image	Note
TS27: cortical layer II	Present	3A TLE3 WT	Expression specific for layers II-V.
TS27: cortical layer III	Present	3A TLE3 WT	Expression specific for layers II-V.
TS27: cortical layer IV	Present	3A TLE3 WT	Expression specific for layers II-V.
TS27: cortical layer V	Present	3A TLE3 WT	Expression specific for layers II-V.

Specimen 3A TLE3 Brn-1-/-: postnatal day 0; Pou3f3^tm1Rmc/Pou3f3^tm1Rmc (more

)

Structure	Level	Image	Note
TS27: cortical layer II	Present	3A TLE3 Brn-1-/-	Expression specific for layers II-V.
TS27: cortical layer III	Present	3A TLE3 Brn-1-/-	Expression specific for layers II-V.
TS27: cortical layer IV	Present	3A TLE3 Brn-1-/-	Expression specific for layers II-V.
TS27: cortical layer V	Present	3A TLE3 Brn-1-/-	Expression specific for layers II-V.

Specimen 3A TLE3 Brn-1-/-/Brn-2-/-: postnatal day 0; Pou3f2^tm1Rsd/Pou3f2^tm1Rsd, Pou3f3^tm1Rmc/Pou3f3^tm1Rmc (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebral cortex	Present	Regionally restricted	3A TLE3 Brn-1-/-/Brn-2-/-	Expression in deeper regions of cortex compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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