Gene Expression Data
Assay Details
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Assay
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Reference:
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J:74124
Kinder SJ, et al., Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity. Int J Dev Biol. 2001;45(1 Spec No):347-55
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7737682
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Gene symbol:
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Gsc
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Gene name:
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goosecoid homeobox
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Probe:
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Gsc probe
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Probe preparation:
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labelled with digoxigenin RNA
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Results
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Specimen
Otx2 mutant gastrula not shown:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Otx2tm1Sla/Otx2tm1Sla
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Age:
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embryonic day 7.5
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo |
Ambiguous |
Regionally restricted |
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Expression in proximal germ layer tissues in 1 of 4 embryos analyzed; no expression in 3 embryos.
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Specimen
4a:
embryonic day 8.5
(more  )
Specimen
4a:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4b:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Foxa2tm1Jrt/Foxa2tm1Jrt
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Weak |
Regionally restricted |
4b
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Weak expression, not localized to midline, in only 1 of 10 Hnf3b mutant embryos.
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Specimen
4c:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Lhx1tm1Bhr/Lhx1tm1Bhr
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Absent |
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4c
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No expression in mutant embryos that formed a truncated head.
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Specimen
4d:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Otx2tm1Sla/Otx2tm1Sla
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Weak |
Regionally restricted |
4d
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Weak expression in anterior axial tissues in some Otx2 mutant embryos.
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Specimen
4e:
embryonic day 8.5; T/ T
(more )
Specimen
4e:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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T/T
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Present |
Regionally restricted |
4e
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Normal anterior expression in T mutant embryos that form head structures.
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Analysis Tools
