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Gene Expression Data
Assay Details
Assay
Reference: J:83935 Zechner D, et al., beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol. 2003 Jun 15;258(2):406-18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736711
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-TuJ1
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 3a: embryonic day 11.5 (more )
Note: Double labeled: red - Tubb3; green - Nes (assay MGI:7736712).
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord neuron Present Regionally restricted 3a Expression in differentiated neurons.
Specimen 3b: embryonic day 11.5; Ctnnb1tm4Wbm/Ctnnb1tm4Wbm, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - Nes (assay MGI:7736712).
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord neuron Present Regionally restricted 3b Proportionately larger area occupied by differentiated neurons compared to control.
Specimen 3c: embryonic day 11.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - Nes (assay MGI:7736712).
Structure Cell Type Level Pattern Image Note
TS19: future spinal cord neuron Present Regionally restricted 3c Relatively small proportion of area occupied by differentiated neurons compared to control.
Specimen 3d: embryonic day 11.5 (more )
Note: Double labeled: red - Tubb3; green - Nes (assay MGI:7736712).
Structure Cell Type Level Pattern Image Note
TS19: midbrain neuron Present Regionally restricted 3d Expression in differentiated neurons.
Specimen 3e: embryonic day 11.5; Ctnnb1tm4Wbm/Ctnnb1tm4Wbm, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - Nes (assay MGI:7736712).
Structure Cell Type Level Pattern Image Note
TS19: midbrain neuron Present Regionally restricted 3e Expression in differentiated neurons.
Specimen 3f: embryonic day 11.5; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - Nes (assay MGI:7736712).
Structure Cell Type Level Pattern Image Note
TS19: midbrain neuron Present Regionally restricted 3f Expression in differentiated neurons.
Specimen 6a: embryonic day 11.0 (more )
Note: Double labeled: red - Tubb3; green - BrdU.
Structure Level Pattern Image Note
TS18: future spinal cord Present 6a
Specimen 6b: embryonic day 11.0; Ctnnb1tm4Wbm/Ctnnb1tm4Wbm, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - BrdU.
Structure Level Pattern Image Note
TS18: future spinal cord Present 6b
Specimen 6c: embryonic day 11.0; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - BrdU.
Structure Level Pattern Image Note
TS18: future spinal cord Present 6c
Specimen 6d: embryonic day 11.0 (more )
Note: Double labeled: red - Tubb3; green - TUNEL.
Structure Level Pattern Image Note
TS18: future spinal cord Present 6d
Specimen 6e: embryonic day 11.0; Ctnnb1tm4Wbm/Ctnnb1tm4Wbm, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - TUNEL.
Structure Level Pattern Image Note
TS18: future spinal cord Present 6e
Specimen 6f: embryonic day 11.0; Ctnnb1tm1Mmt/Ctnnb1+, Tg(Pou3f4-cre)32Cren/? (more )
Note: Conditional mutant. Double labeled: red - Tubb3; green - TUNEL.
Structure Level Pattern Image Note
TS18: future spinal cord Present 6f
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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