Gene Expression Data
Assay Details
Assay
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Reference:
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J:279388
Weiss AC, et al., Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7718883
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Gene symbol:
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Kit
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Gene name:
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KIT proto-oncogene receptor tyrosine kinase
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Results
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Specimen
S5C:
embryonic day 18.5; Gata2tm1Sac/?
(more )
Note: Littermates without the Tbx18cre were used as control.
Specimen
S5C:
(close )
Genetic Background:
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involves: 129S1/SvImJ * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Gata2tm1Sac/?
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Littermates without the Tbx18cre were used as control.
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Structure |
Level |
Pattern |
Image |
Note |
TS26: renal pelvis |
Present |
Regionally restricted |
S5C
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Kit is a marker for interstitial Cajal-like cells in the renal pelvis.
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Specimen
S5D:
(close )
Genetic Background:
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involves: 129S1/SvImJ * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Gata2tm1Sac/Gata2tm1Sac Tbx18tm4(cre)Akis/Tbx18+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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Structure |
Level |
Pattern |
Image |
Note |
TS26: renal pelvis |
Present |
Regionally restricted |
S5D
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Expression was unchanged in the Gata2cKO renal pelvis interstitial Cajal-like cells.
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Specimen
S5E:
embryonic day 18.5; Gata2tm1Sac/?
(more )
Specimen
S5E:
(close )
Genetic Background:
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involves: 129S1/SvImJ * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Gata2tm1Sac/?
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS26: ureteral mesenchyme |
Present |
Regionally restricted |
S5E
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Expression was detected in the outer mesenchymal region.
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Specimen
S5F:
(close )
Genetic Background:
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involves: 129S1/SvImJ * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Gata2tm1Sac/Gata2tm1Sac Tbx18tm4(cre)Akis/Tbx18+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: ureteral mesenchyme |
Present |
Regionally restricted |
S5F
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Expression was unchanged in the Gata2cKO outer mesenchymal region.
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