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Gene Expression Data
Assay Details
Assay
Reference: J:279388 Weiss AC, et al., Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7718877
Gene symbol: Hcn3
Gene name: hyperpolarization-activated, cyclic nucleotide-gated K+ 3
Antibody: Anti-HCN3
Results
Specimen S5A: embryonic day 18.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Level Pattern Image Note
TS26: renal pelvis Present Regionally restricted S5A Hcn3 is a marker for pacemaker cells in the renal pelvis.
Specimen S5B: embryonic day 18.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: renal pelvis Present Regionally restricted S5B Expression was unchanged in the Gata2cKO renal pelvis pacemaker cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory