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Gene Expression Data
Assay Details
Assay
Reference: J:333283 Guan N, et al., Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency. Kidney Int. 2022 Jul;102(1):108-120
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7718728
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Results
Specimen 5a Cre-: embryonic day 13.5; Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Structure Level Pattern Image Note
TS21: cap mesenchyme Present 5a SIX2 left
Specimen 5a Six2-Qpc-/-: embryonic day 13.5; Tg(Six2-EGFP/cre)1Amc/0, Uqcrqtm1.1Ncdl/Uqcrq+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cap mesenchyme Present 5a SIX2 right Reduced number of positive caps compared with the control.
Specimen S4C Cre-: postnatal day 0; Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Double labeled: purple - Six2; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS27: cap mesenchyme Present S4C SIX2 left
Specimen S4C Hoxb7-Qpc-/-: postnatal day 0; Tg(Hoxb7-cre)13Amc/0, Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Conditional mutant. Double labeled: purple - Six2; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS27: cap mesenchyme Present S4C SIX2 right Similar as the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory