| Assay |
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| Results |
(a) Values are listed as levels of the Col2a1 IIB isoform expressed as a percentage of the total copy number of IIA, IIB, IIC and IID in chondrocytes from wild type, ki/+ and ki/ki cartilage at each time point. Strength was assigned by curator as follows: >= 90% = strong; 10-89% = present; 1-9.9% = weak; 0.1-0.9% = trace; <0.09 = ambiguous; 0.00 = absent. (b) 0.45%. Isoform IIB mRNA was barely detectable at E12.5. (c) 0.33% (d) 0.01% (e) 72.07%. By E16.5, the splicing switch from isoforms IIA/IID to IIB had occurred in wild type. (f) 54.82% (g) 47.15% (h) 92.78%. From P0 onwards, over 90% of mRNA transcripts generated in wild type chondrocytes were isoform IIB. (i) 89.08% (j) 62.93% (k) 92.89% (l) 91.81% (m) 78.80% (n) 99.00% (o) 90.30% (p) 71.12% (q) 99.25% (r) 91.31% (s) 77.42% (t) 94.06% (u) 62.62% (v) 48.14% |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/30/2025 MGI 6.24 |
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