Hoxd11 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:237482 Amandio AR, et al., Hotair Is Dispensible for Mouse Development. PLoS Genet. 2016 Dec;12(12):e1006232
Assay type:	RNA in situ
MGI Accession ID:	MGI:7707843
Gene symbol:	Hoxd11
Gene name:	homeobox D11

Probe:	Hoxd11 cDNA1
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

6B wt Hoxd11 ©

Specimen 6B wt: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: paraxial mesenchyme	Present	Regionally restricted	6B wt Hoxd11	Rostral limits of expression were indicated.
TS20: spinal cord	Present	Regionally restricted	6B wt Hoxd11	Rostral limits of expression were indicated.

Specimen 6B Del(Hotair)-/-: embryonic day 12.5; Hotair^tm1.1Hyc/Hotair^tm1.1Hyc (more

)

Structure	Level	Pattern	Image	Note
TS20: paraxial mesenchyme	Present	Regionally restricted	6B Del(Hotair)-/- Hoxd11	No detectable difference in the anterior limit of expression was observed in the mutant compared with wild type.
TS20: spinal cord	Present	Regionally restricted	6B Del(Hotair)-/- Hoxd11	No detectable difference in the anterior limit of expression was observed in the mutant compared with wild type.

Specimen 6C wt Hoxd11;MyoD: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: paraxial mesenchyme	Present	Regionally restricted	6C wt Hoxd11;MyoD	Expression was detected at the level of somite 29 and caudally.
TS20: spinal cord	Present	Regionally restricted	6C wt Hoxd11;MyoD	Expression was detected at the level of somite 29 and caudally.

Specimen 6C Del(Hotair)-/- Hoxd11;MyoD: embryonic day 12.5; Hotair^tm1.1Hyc/Hotair^tm1.1Hyc (more

)

Structure	Level	Pattern	Image	Note
TS20: paraxial mesenchyme	Present	Regionally restricted	6C Del(Hotair)-/- Hoxd11;MyoD	No detectable difference in the anterior limit, intensity of the signal, or the spatial pattern of expression was observed in the mutant compared with wild type.
TS20: spinal cord	Present	Regionally restricted	6C Del(Hotair)-/- Hoxd11;MyoD	No detectable difference in the anterior limit, intensity of the signal, or the spatial pattern of expression was observed in the mutant compared with wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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