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Gene Expression Data
Assay Details
Assay
Reference: J:250104 Flodby P, et al., The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. Am J Respir Cell Mol Biol. 2016 Jul;55(1):135-49
Assay type: Western blot
MGI Accession ID: MGI:7704083
Gene symbol: Sftpc
Gene name: surfactant associated protein C
Antibody: anti-proSP-C (AB3786)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 3A Pro-SFTPC
 Sample Information Bands Other Sample Information
Lane AgeStructure 23 kDa (b) 21 kDa (b) Genetic BackgroundMutant Allele(s)Sex Note
f/f E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1AleeNot Specified
f/f E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1AleeNot Specified
f/f E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1AleeNot Specified
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
cKO E18.0 (a) TS26: lung Present Present involves: 129 * C57BL/6 * DBA/2 Hspa5tm1Alee/Hspa5tm1Alee, Tg(Sftpc-cre)1Blh/0Not Specified Conditional mutant.
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) An approximately 60% decrease in expression in the mutant mice compared with controls (quantified in Fig 3B).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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