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Gene Expression Data
Assay Details
Assay
Reference: J:350502 Zhang J, et al., CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment. Nat Commun. 2024 Jul 1;15(1):5524
Assay type: RT-PCR
MGI Accession ID: MGI:7665345
Gene symbol: Ctcf
Gene name: CCCTC-binding factor
Probe: Ctcf-pF, Ctcf-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh.
Results
Image: S1e ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
NSC +/+ Cultured cells: no data stored
NSC +/R567W Cultured cells: no data stored
NSC R567W/R567W Cultured cells: no data stored
Neuron +/+ Cultured cells: no data stored
Neuron +/R567W Cultured cells: no data stored
Neuron R567W/R567W Cultured cells: no data stored
Brain +/+ E18.5 TS26: brain Present Not Specified; total RNA C57BL/6N Not Specified
Brain +/R567W E18.5 TS26: brain Present Not Specified; total RNA C57BL/6N-Ctcfem1Hyao Ctcfem1Hyao/Ctcf+Not Specified
Brain R567W/R567W E18.5 TS26: brain Present Not Specified; total RNA C57BL/6N-Ctcfem1Hyao Ctcfem1Hyao/Ctcfem1HyaoNot Specified
Heart +/+ E18.5 TS26: heart Present Not Specified; total RNA C57BL/6N Not Specified
Heart +/R567W E18.5 TS26: heart Present Not Specified; total RNA C57BL/6N-Ctcfem1Hyao Ctcfem1Hyao/Ctcf+Not Specified
Heart R567W/R567W E18.5 TS26: heart Present Not Specified; total RNA C57BL/6N-Ctcfem1Hyao Ctcfem1Hyao/Ctcfem1HyaoNot Specified
Lung +/+ E18.5 TS26: lung Present Not Specified; total RNA C57BL/6N Not Specified
Lung +/R567W E18.5 TS26: lung Present Not Specified; total RNA C57BL/6N-Ctcfem1Hyao Ctcfem1Hyao/Ctcf+Not Specified
Lung R567W/R567W E18.5 TS26: lung Strong (a) Not Specified; total RNA C57BL/6N-Ctcfem1Hyao Ctcfem1Hyao/Ctcfem1HyaoNot Specified
Notes:
(a) Statistically significant increase in expression compared to wild type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory