Avp RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171421 Vandunk C, et al., Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus. J Neurosci. 2011 Apr 27;31(17):6457-67
Assay type:	RNA in situ
MGI Accession ID:	MGI:7660861
Gene symbol:	Avp
Gene name:	arginine vasopressin

Probe:	Avp probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

2A AVP ©

Specimen 2A: postnatal day 15 (more

)

Structure	Level	Pattern	Image	Note
TS28: suprachiasmatic nucleus	Present	Regionally restricted	2A AVP	Expression was restricted to the outer area of the suprachiasmatic nucleus.

Specimen not shown: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: supraoptic nucleus	Strong
TS25: suprachiasmatic nucleus	Present

Specimen not shown: postnatal (more

)

Structure	Level	Pattern	Image	Note
TS28: suprachiasmatic nucleus	Present

5_AVP Rora^+/+ ©

Specimen 5 Rora^+/+: postnatal day 15 (more

)

Structure	Level	Pattern	Image	Note
TS28: suprachiasmatic nucleus	Present		5_AVP Rora^+/+

Specimen 5 Rora^sg/sg: postnatal day 15; Rora^sg/Rora^sg (more

)

Structure	Level	Pattern	Image	Note
TS28: suprachiasmatic nucleus	Present		5_AVP Rora^sg/sg	The spatial mRNA expression patterns within the suprachiasmatic nucleus remained unaltered in all P15 sg/sg mutants (four of four) compared with wild-type littermates.

8A top AVP ©

Specimen 8A Six3^flox/flox;Nestin-cre^-: embryonic day 18.5; Six3^tm2Gco/Six3^tm2Gco (more

)

Structure	Level	Pattern	Image	Note
TS26: suprachiasmatic nucleus	Present	Regionally restricted	8A top AVP

Specimen 8A Six3^flox/flox;Nestin-cre⁺: embryonic day 18.5; Six3^tm2Gco/Six3^tm2Gco, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: hypothalamus	Absent		8A bottom AVP	There was no expression in the ventral anterior hypothalamus of the mutant.

Specimen 8B Six3^flox/flox;Nestin-cre^- aPV: embryonic day 18.5-19.5; Six3^tm2Gco/Six3^tm2Gco (more

)

Structure	Level	Pattern	Image	Note
TS26: paraventricular hypothalamic nucleus	Present	Regionally restricted	8B AVP top aPV	Expression was detected in anterior paraventricular hypothalamic nuclei.

Specimen 8B Six3^flox/flox;Nestin-cre⁺ aPV: embryonic day 18.5-19.5; Six3^tm2Gco/Six3^tm2Gco, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: paraventricular hypothalamic nucleus	Present	Regionally restricted	8B AVP bottom aPV	Mutant mice retained expression in the anterior paraventricular hypothalamic nuclei.

Specimen 8B Six3^flox/flox;Nestin-cre^- SON: embryonic day 18.5-19.5; Six3^tm2Gco/Six3^tm2Gco (more

)

Structure	Level	Pattern	Image	Note
TS26: supraoptic nucleus	Present		8B AVP top SON left , 8B AVP top SON right

Specimen 8B Six3^flox/flox;Nestin-cre⁺ SON: embryonic day 18.5-19.5; Six3^tm2Gco/Six3^tm2Gco, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: supraoptic nucleus	Present		8B AVP bottom SON left , 8B AVP bottom SON right	Mutant mice retained expression in the supraoptic nucleus.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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