Ascl2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:93446 Guzman-Ayala M, et al., Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment. Proc Natl Acad Sci U S A. 2004 Dec 2;101(44):15656-60
Assay type:	RNA in situ
MGI Accession ID:	MGI:7660819
Gene symbol:	Ascl2
Gene name:	achaete-scute family bHLH transcription factor 2

Probe:	Mash-2 probe
Probe preparation:	Antisense RNA

Results

Specimen 1B control: embryonic day 7.5 (more

)

Structure	Level	Pattern	Image	Note
TS11: ectoplacental cone	Present		1B Mash2 control

Specimen 1B class I DKO: embryonic day 7.5; Furin^tm1Ajmr/Furin^tm1Ajmr, Pcsk6^tm1Rob/Pcsk6^tm1Rob (more

)

Structure	Level	Pattern	Image	Note
TS11: ectoplacental cone	Present		1B Mash2 class I	In this mutant the expression domain had expanded toward the epiblast boundary.
TS11: extraembryonic ectoderm	Present		1B Mash2 class I	In this mutant the expression domain had expanded toward the epiblast boundary.

Specimen 1B class II DKO: embryonic day 7.5; Furin^tm1Ajmr/Furin^tm1Ajmr, Pcsk6^tm1Rob/Pcsk6^tm1Rob (more

)

Structure	Level	Pattern	Image	Note
TS11: ectoplacental cone	Present		1B Mash2 class II	In this mutant the expression domain had expanded toward the epiblast boundary.
TS11: extraembryonic ectoderm	Present		1B Mash2 class II	In this mutant the expression domain had expanded toward the epiblast boundary.

Specimen 1B Nodal^-/-: embryonic day 7.5; Nodal^tm1Rob/Nodal^tm1Rob (more

)

Structure	Level	Pattern	Image	Note
TS11: ectoplacental cone	Present		1B Mash2 Nodal^-/-	In this mutant the expression domain had expanded toward the epiblast boundary.
TS11: extraembryonic ectoderm	Present		1B Mash2 Nodal^-/-	In this mutant the expression domain had expanded toward the epiblast boundary.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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