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Gene Expression Data
Assay Details
Assay
Reference: J:192375 Ishikawa T, et al., Transient expression of Xpn, an XLMR protein related to neurite extension, during brain development and participation in neurite outgrowth. Neuroscience. 2012 Jul 12;214:181-91
Assay type: RNA in situ
MGI Accession ID: MGI:7657403
Gene symbol: Nexmif
Gene name: neurite extension and migration factor
Results
Specimen 5Aa: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: brainstem neuron Present Regionally restricted 5Aa Expression was in type-I neurons distributed throughout the lower brainstem.
TS20: cortical plate cerebral cortex neuron Weak Regionally restricted 5Aa Type-II neurons were lightly labeled cells in the cortical plate on E12.5.
TS20: telencephalon neuron Weak Regionally restricted 5Aa Lightly labeled type III neurons were detected in the primordium of hippocampal regions CA1-CA3
TS20: brain glial cell Absent 5Aa

Specimen 5Ab: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: cortical plate cerebral cortex neuron Weak 5Ab Type-II neurons were lightly labeled cells in the cortical plate on E12.5.

Specimen 5Ac: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: brainstem neuron Present Regionally restricted 5Ac Type I neurons were labeled in the entire brainstem.
TS22: hypothalamus neuron Present Regionally restricted 5Ac Type I neurons extended rostrally into the upper brainstem (thalamus and hypothalamus).
TS22: thalamus neuron Present Regionally restricted 5Ac Type I neurons extended rostrally into the upper brainstem (thalamus and hypothalamus).
TS22: cortical plate cerebral cortex neuron Present Regionally restricted 5Ac Labeling in type-II neurons increased.
TS22: brain glial cell Absent 5Ac

Specimen 5Ad: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: cortical plate cerebral cortex neuron Present Regionally restricted 5Ad Labeling in type-II neurons increased.

Specimen 5Ae: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: brainstem neuron Weak Regionally restricted 5Ae The signal intensity in type-I brainstem neurons decreased markedly.
TS25: cerebral cortex intermediate zone cerebral cortex neuron Strong Regionally restricted 5Ae Strong labeling was observed in the type-II neurons.
TS25: cortical plate cerebral cortex neuron Strong Regionally restricted 5Ae Strong labeling was observed in the type-II neurons.
TS25: hippocampus neuron Strong Regionally restricted 5Ae Strongly labeled neurons were detected in the developing CA1-CA3 region.
TS25: brain glial cell Absent 5Ae

Specimen 5Af: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: cerebral cortex intermediate zone cerebral cortex neuron Strong Regionally restricted 5Af Strong labeling was observed in the type-II neurons.
TS25: cortical plate cerebral cortex neuron Strong Regionally restricted 5Af Strong labeling was observed in the type-II neurons.

Specimen 5Ag: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: brainstem neuron Weak Single cells 5Ag Very few positive cells were observed.
TS28: cerebral cortex cerebral cortex neuron Weak Widespread 5Ag Lightly labeled neurons were disseminated throughout the cerebral cortex.
TS28: brain glial cell Absent 5Ag

Specimen 5Ah: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex cerebral cortex neuron Weak Widespread 5Ah Lightly labeled neurons were disseminated throughout the cerebral cortex.

Specimen 5Ai: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: brainstem neuron Weak Single cells 5Ai Very few positive cells were observed.
TS28: cerebral cortex cerebral cortex neuron Weak Widespread 5Ai Lightly labeled neurons were disseminated throughout the cerebral cortex.
TS28: ventral posterior medial thalamic nucleus neuron Present 5Ai
TS28: brain glial cell Absent 5Ai

Specimen 5Aj: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex cerebral cortex neuron Weak Widespread 5Aj Lightly labeled neurons were disseminated throughout the cerebral cortex.

Specimen 5B E14.5: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: main olfactory bulb mitral cell layer mitral cell Weak 5B E14.5

Specimen 5B E17.5: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: main olfactory bulb mitral cell layer mitral cell Present 5B E17.5

Specimen 5B P7: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: main olfactory bulb mitral cell layer mitral cell Present 5B P7 Expression increased markedly in mitral cells after birth.

Specimen 5B Adult: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: main olfactory bulb mitral cell layer mitral cell Present 5B Adult Maximum expression level in mitral cells was reached in adulthood.

Specimen 5C E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebellum Absent 5C E14.5

Specimen 5C E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebellum Absent 5C E17.5

Specimen 5C P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Present 5C P7
TS28: deep cerebellar nucleus Present 5C P7

Specimen 5C Adult: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum cerebellar neuron Absent 5C Adult
TS28: cerebellum Purkinje cell Absent 5C Adult

Specimen 5D E17.5: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: hippocampus neuron Strong Regionally restricted 5D E17.5 Strongly labeled neurons were detected in the developing CA1-CA3 region.
TS25: dentate gyrus dentate gyrus granule cell Weak 5D E17.5

Specimen 5D P7: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: hippocampus CA1 hippocampal CA1-3 neuron Strong 5D P7
TS28: hippocampus CA2 hippocampal CA1-3 neuron Strong 5D P7
TS28: hippocampus CA3 hippocampal CA1-3 neuron Strong 5D P7
TS28: dentate gyrus granule cell layer dentate gyrus granule cell Present 5D P7 Signal in the dentate gyrus granule cells increased dramatically after P7.

Specimen 5D Adult: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: hippocampus CA1 hippocampal CA1-3 neuron Strong 5D Adult
TS28: hippocampus CA1 hippocampal pyramidal neuron Strong 5D Adult
TS28: hippocampus CA2 hippocampal CA1-3 neuron Strong 5D Adult
TS28: hippocampus CA2 hippocampal pyramidal neuron Strong 5D Adult
TS28: hippocampus CA3 hippocampal CA1-3 neuron Strong 5D Adult
TS28: hippocampus CA3 hippocampal pyramidal neuron Strong 5D Adult
TS28: dentate gyrus granule cell layer dentate gyrus granule cell Present 5D Adult Maximum expression level in dentate gyrus granule cells was detected in the adult.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory