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Gene Expression Data
Assay Details
Assay
Reference: J:348632 Huang B, et al., Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease. Cell Stem Cell. 2024 Apr 22;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645920
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2 (11562-1-AP)
Detection system: Secondary antibody
Assay notes: The authors reported using two different antibodies; it is possible MGI:7471517 was used to obtain some or all of these data.
Results
Specimen 1C: embryonic day 13.5 (more )
Note: Triple labeled: red - Six2; blue - Krt8 (assay MGI:7645909); green - p-p38.
Structure Level Pattern Image Note
TS21: cap mesenchyme Present Regionally restricted 1C SIX2 , 1C merge Expression is present in nephron progenitor cells.
Specimen S3A - E14.5: embryonic day 14.5 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:7645909); blue - DAPI.
Structure Level Pattern Image Note
TS22: cap mesenchyme Present Regionally restricted S3A E14.5 Expression is present in nephron progenitor cells.
Specimen S3A - P3: postnatal day 3 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:7645909); blue - DAPI.
Structure Level Pattern Image Note
TS27: metanephros Absent S3A P3 Apparent signal is due to non-specific antibody binding.
Specimen S3A - P4: postnatal day 4 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:7645909); blue - DAPI.
Structure Level Pattern Image Note
TS28: metanephros Absent S3A P4 Apparent signal is due to non-specific antibody binding.
Specimen S3A - P5: postnatal day 5 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:7645909); blue - DAPI.
Structure Level Pattern Image Note
TS28: metanephros Absent S3A P5 Apparent signal is due to non-specific antibody binding.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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