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Gene Expression Data
Assay Details
Assay
Reference: J:84852 Imanaka-Yoshida K, et al., The dynamic expression of tenascin-C and tenascin-X during early heart development in the mouse. Differentiation. 2003 Jun;71(4-5):291-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645232
Gene symbol: Tnc
Gene name: tenascin C
Antibody: anti-TNC (4F10TT)
Detection system: horseradish peroxidase
Results
Specimen 2C: embryonic day 9.5; Tnctm1Sia/Tnc+ (more )
Note: Double labeled: brown - Tnc protein; blue - Tnc reporter (assay MGI:7645230).
Structure Level Pattern Image Note
TS15: atrioventricular endocardial cushion Strong Regionally restricted 2C Strong expression in subendocardial regions of atrioventricular and conotruncal cushion tissue.
TS15: outflow tract endocardial cushion Strong Regionally restricted 2C Strong expression in subendocardial regions of atrioventricular and conotruncal cushion tissue.
Specimen 2D: embryonic day 9.5; Tnctm1Sia/Tnc+ (more )
Note: Double labeled: brown - Tnc protein; blue - Tnc reporter (assay MGI:7645230).
Structure Cell Type Level Pattern Image Note
TS15: outflow tract endocardial cushion fetal cardiomyocyte Present Regionally restricted 2D In conotruncal cushion, expression in cardiomyocytes.
TS15: outflow tract endocardial cell Present Regionally restricted 2D Expression in endocardial cells lining endothelium and migrating into cardiac jelly of outflow tract.
Specimen 2F: embryonic day 9.5; Tnctm1Sia/Tnc+ (more )
Note: Double labeled: brown - Tnc protein; blue - Tnc reporter (assay MGI:7645230).
Structure Cell Type Level Pattern Image Note
TS15: atrioventricular canal endocardial lining endocardial cell Present Regionally restricted 2F Expression in endocardial cells lining endothelium of atrioventricular canal.
TS15: atrioventricular canal endocardial cell Present Regionally restricted 2F Expression in endocardial cells migrating into cardiac jelly of endocardial canal.
Specimen 2I: embryonic day 9.5; Tnctm1Sia/Tnc+ (more )
Note: Double labeled: brown - Tnc protein; blue - Tnc reporter (assay MGI:7645230).
Structure Cell Type Level Pattern Image Note
TS15: proepicardium cardiac mesenchymal cell Strong Regionally restricted 2I Strong expression in mesenchymal cells of proepicardial organ (PEO).
TS15: pericardium Present Regionally restricted 2I Expression in inner surfaces of pericardium.
Specimen 4A: embryonic day 11.5; Tnctm1Sia/Tnc+ (more )
Note: Double labeled: brown - Tnc protein; blue - Tnc reporter (assay MGI:7645230).
Structure Level Pattern Image Note
TS19: visceral pericardium Present Regionally restricted 4A Expression in epicardial layer of diaphragm.
Specimen 4B: embryonic day 11.5; Tnctm1Sia/Tnctm1Sia (more )
Note: Double labeled: brown - Tnc protein; blue - Tnc reporter (assay MGI:7645230).
Structure Level Pattern Image Note
TS19: visceral pericardium Absent 4B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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